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    A study to compare “ipatasertib + chemotherapy” with “placebo + chemotherapy” – in patients with inoperable or metastatic triple negative breast cancer

    A Study Assessing the Safety and Efficacy of Adding Ipatasertib to Paclitaxel Treatment in Participants With Breast Cancer That Has Spread Beyond the Initial Site, and the Cancer Does Not Have Certain Hormonal Receptors

    • Cancer
    • Breast Cancer
    • Breast Neoplasms
    • Tumor

    Basic Details

    Gender
    Female
    Age
    ≥18 Years
    Healthy Volunteers
    No
    Sponsor Genentech, Inc.
    Phase Phase 2
    Study Identifier NCT02162719, GO29227, 2014-000469-35

    This clinical trial was done to study a new medicine called, “ipatasertib”, for the treatment of patients with “triple negative breast cancer” or “TNBC” for short. This study was done to find out if adding ipatasertib to chemotherapy improved the outcome for patients with TNBC. Researchers also wanted to know the effect of ipatasertib on patients with TNBC who had certain genetic mutations. One hundred and twenty-four patients took part in this study at 69 study centers in eight countries.

    The source of the below information is public registry websites such as ClinicalTrials.gov, EuClinicalTrials.eu, ISRCTN.com, etc.. It has been summarised and edited into simpler language. For more information about this clinical study see the For Expert tab on the specific ForPatients page or follow these links to https://clinicaltrials.gov and/or https://euclinicaltrials.eu and/or https://www.isrctn.com.

    The information is taken directly from public registry websites such as ClinicalTrials.gov, EuClinicalTrials.eu, ISRCTN.com, etc., and has not been edited.

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      What is Clinical Research?

      In clinical research, volunteers, researchers, and medical professionals work together toward a shared goal: better treatment outcomes for patients. Clinical trials are vital to their process. They are carefully designed and follow approved protocols.