A Study To Investigate The Safety Of RO7248824 in Children With Angelman Syndrome And To Understand The Way The Body Processes The Investigational Therapy

A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7248824 in Participants With Angelman Syndrome (AS)

Neurodevelopmental Disorder
Angelman Syndrome

Results
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Study results

LPS BP41674 TANGELO Final Results December 2025 English (PDF, 0.6 MB)

LPS BP41674 TANGELO Final Results December 2025 Dutch (PDF, 0.4 MB)

LPS BP41674 TANGELO Final Results December 2025 Italian (PDF, 0.4 MB)

LPS BP41674 TANGELO Final Results December 2025 Spanish (PDF, 1.1 MB)

What is Clinical Research?

In clinical research, volunteers, researchers, and medical professionals work together toward a shared goal: better treatment outcomes for patients. Clinical trials are vital to their process. They are carefully designed and follow approved protocols.

A Study To Investigate The Safety Of RO7248824 in Children With Angelman Syndrome And To Understand The Way The Body Processes The Investigational Therapy

Study results

LPS BP41674 TANGELO Final Results December 2025 English (PDF, 0.6 MB)

LPS BP41674 TANGELO Final Results December 2025 Dutch (PDF, 0.4 MB)

LPS BP41674 TANGELO Final Results December 2025 Italian (PDF, 0.4 MB)

LPS BP41674 TANGELO Final Results December 2025 Spanish (PDF, 1.1 MB)

What is Clinical Research?

For the latest version of this information please go to www.forpatients.roche.com

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A Study To Investigate The Safety Of RO7248824 in Children With Angelman Syndrome And To Understand The Way The Body Processes The Investigational Therapy

For the latest version of this information please go to www.forpatients.roche.com